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The landscape of HIV drugs is constantly evolving, and as we navigate 2025, it's crucial for us healthcare professionals to understand the current mechanisms driving these life-saving therapies. You and I know that effective HIV management hinges on suppressing the virus, improving immune function, and ultimately enhancing the quality of life for individuals living with HIV. Let's delve into the fascinating ways these medications work.

Understanding the Arsenal: Key Drug Classes

To effectively combat HIV, we utilize several classes of HIV drugs, each targeting a specific stage of the viral lifecycle. These include Nucleoside Reverse Transcriptase Inhibitors (NRTIs), Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs), Protease 1 Inhibitors (PIs), Integrase Inhibitors (INIs), and entry inhibitors. 2 These classes often form the backbone of combination therapies, a cornerstone of modern HIV treatment. 

Disrupting Replication: The Role of Reverse Transcriptase Inhibitors

You see, for HIV to replicate, it needs to convert its RNA into DNA, a process carried out by an…

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